A sensitive method for rapid determination of 256 semi-volatile organic compounds(SVOCs)in water by solid-phase extraction and GC-MS/MS
简介：A trace analytical method based on solid-phase extraction gas chromatography-tandem mass spectrometry(SPE-GC-MS/MS)was developed for the rapid detection of 256 semi-volatile organic compounds(SVOCs),including 25 polycyclic aromatic hydrocarbons(PAHs),70 polychlorinated biphenyls(PCBs),123 pesticides,20 phthalate esters(PAEs),4 organophosphate esters(OPEs),9 synthetic musks(SMs),and 5 UV filters(UVs)in water.No-tably,this method provided a decent linearity of calibration standards(R2＞0.999),excellent method limits of quantification(MLOQs)(0.12-11.41 ng/L),satisfactory matrix spiking recovery rates(60.4％-126％),and high precision(intra-day relative standard deviations(RSDs):1.0％-10.0％,inter-day RSDs:3.0％-15.0％,and inter-week RSDs:3.4％-15.7％),making it suitable for trace-level studies.Statistical analysis revealed that SVOCs with higher volatility exhibited enhanced recovery rates.Validation of the methodology involved analyzing SVOCs in real spring water and river water samples.Twenty-seven SVOCs were detected in spring water and 58 in river water,with an average concentration of 631.73 and 16,095 ng/L,respectively.Among the detected SVOCs,PAEs constituted the predominant proportion.This study underscored the presence of SVOCs contamination specifi-cally within the spring water,although SVOCs concentrations in river water were significantly greater than those found in spring water.In summary,this sensitive method based on SPE-GC-MS/MS was successfully developed and validated for the rapid analysis of a diverse array of 256 SVOCs at trace levels in water,including not only the traditional highly valued PAHs,PCBs,pesticides,and PAEs,but also the emerging OPEs,UVs,and SMs.展开
